Comparing SpringWorks Therapeutics (NASDAQ:SWTX) & MeiraGTx (NASDAQ:MGTX)

SpringWorks Therapeutics (NASDAQ:SWTX) and MeiraGTx (NASDAQ:MGTX) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their dividends, analyst recommendations, earnings, institutional ownership, valuation, profitability and risk.

Institutional and Insider Ownership

75.5% of SpringWorks Therapeutics shares are held by institutional investors. Comparatively, 43.9% of MeiraGTx shares are held by institutional investors. 51.2% of SpringWorks Therapeutics shares are held by company insiders. Comparatively, 17.4% of MeiraGTx shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Earnings & Valuation

This table compares SpringWorks Therapeutics and MeiraGTx’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
SpringWorks Therapeutics N/A N/A -$58.31 million ($3.55) -10.71
MeiraGTx $13.29 million 42.56 -$54.75 million ($1.65) -9.18

MeiraGTx has higher revenue and earnings than SpringWorks Therapeutics. SpringWorks Therapeutics is trading at a lower price-to-earnings ratio than MeiraGTx, indicating that it is currently the more affordable of the two stocks.


This table compares SpringWorks Therapeutics and MeiraGTx’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
SpringWorks Therapeutics N/A N/A N/A
MeiraGTx -313.70% -29.96% -17.49%

Analyst Recommendations

This is a breakdown of current recommendations and price targets for SpringWorks Therapeutics and MeiraGTx, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SpringWorks Therapeutics 0 0 6 0 3.00
MeiraGTx 0 0 2 0 3.00

SpringWorks Therapeutics currently has a consensus target price of $44.60, indicating a potential upside of 17.28%. MeiraGTx has a consensus target price of $42.50, indicating a potential upside of 180.71%. Given MeiraGTx’s higher probable upside, analysts clearly believe MeiraGTx is more favorable than SpringWorks Therapeutics.


SpringWorks Therapeutics beats MeiraGTx on 6 of the 11 factors compared between the two stocks.

About SpringWorks Therapeutics

SpringWorks Therapeutics, Inc., a clinical-stage biopharmaceutical company, acquires, develops, and commercializes medicines for underserved patient populations suffering from rare diseases and cancer. Its advanced product candidate is nirogacestat, an oral small molecule gamma secretase inhibitor that is in Phase 3 clinical trials for the treatment of desmoid tumors. The company is also developing mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas; and Nirogacestat + belantamab mafodotin, which is in Phase 1b clinical trials for the treatment of relapsed or refractory multiple myeloma. In addition, it is developing Mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trials in patients with advanced or refractory solid tumors; and BGB-3245, an investigational oral selective small molecule inhibitor of specific BRAF driver mutations and genetic fusions, which is in preclinical studies in a range of tumor models with BRAF mutations or fusions. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline plc to develop combination approaches with nirogacestat and mirdametinib, as well as other standalone medicines. SpringWorks Therapeutics, Inc. was founded in 2017 and is headquartered in Stamford, Connecticut.

About MeiraGTx

MeiraGTx Holdings plc, a clinical-stage gene therapy company, focusing on developing treatments for patients living with serious diseases. The company develops various therapies for ocular diseases, including rare inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; neurodegenerative diseases, such as amyothrophic lateral sclerosis; and Parkinson's diseases. Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program. The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology. The company was founded in 2015 and is headquartered in New York, New York.

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