Personalis (NASDAQ:PSNL) versus Progenity (NASDAQ:PROG) Financial Review

Personalis (NASDAQ:PSNL) and Progenity (NASDAQ:PROG) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, earnings, analyst recommendations, valuation, institutional ownership, dividends and risk.

Analyst Recommendations

This is a breakdown of recent recommendations for Personalis and Progenity, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Personalis 0 0 3 0 3.00
Progenity 0 0 4 0 3.00

Personalis currently has a consensus target price of $20.00, indicating a potential upside of 14.88%. Progenity has a consensus target price of $13.75, indicating a potential upside of 50.93%. Given Progenity’s higher possible upside, analysts plainly believe Progenity is more favorable than Personalis.

Valuation and Earnings

This table compares Personalis and Progenity’s gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Personalis $65.21 million 8.47 -$25.08 million ($1.39) -12.53
Progenity N/A N/A N/A N/A N/A

Progenity has lower revenue, but higher earnings than Personalis.


This table compares Personalis and Progenity’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Personalis -40.60% -26.28% -17.28%
Progenity N/A N/A N/A

Insider & Institutional Ownership

60.9% of Personalis shares are owned by institutional investors. 8.2% of Personalis shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.


Progenity beats Personalis on 5 of the 8 factors compared between the two stocks.

Personalis Company Profile

Personalis, Inc. operates as a cancer genomics company worldwide. The company provides sequencing and data analysis services to support the development of cancer therapies. It offers NeXT platform, a clinical-grade, next generation sequencing and analysis platform that enables the development of ImmunoID NeXT tumor biopsy and liquid biopsy, as well as provides analysis of tumor and immune microenvironment from a single limited tissue sample, tumor molecular profiling for cancer patients, and anticipates future cancer biomarkers. The company also provides accuracy and content enhanced platform (ACE) that enhances nucleic acid preparation processes and combines it with patented assay and sequencing methods. ACE Platform offers multiple products and services, such as ACE extended cancer panel for DNA and RNA, and ACE cancer research Exome and Transcriptome. In addition, it develops NeXT Dx test, which helps oncologists to identify potential therapies and clinical trial options for cancer patients, as well as offers whole genome sequencing, which provides DNA sequencing and data analysis services; and ACE CancerPlus Test. The company also provides a liquid biopsy assay that analyzes various human genes versus the more narrowly focused liquid biopsy assays that are currently available. It serves approximately 50 biopharmaceutical customers, including a range of pharmaceutical companies. The company was founded in 2011 and is headquartered in Menlo Park, California.

Progenity Company Profile

Progenity, Inc., a biotechnology company, provides complex molecular and specialized testing services to physicians, clinicians, and their patients in the United States. It offers testing services for common hereditary disorders, cystic fibrosis, spinal muscular atrophy, fragile X syndrome, and Jewish genetic diseases; pan-ethnic carrier screening services; non-invasive prenatal, miscarriage, and pharmacogenetic testing services; and ovarian assessment reports for women. The company also provides pediatric testing services. Progenity, Inc. was formerly known as Ascendant MDX, Inc. and changed its name to Progenity, Inc. in November, 2013. The company was incorporated in 2012 and is based in San Diego, California with a laboratory in Ann Arbor, Michigan. It has a bill payment location in Detroit, Michigan.

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